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Postpartum depression medication and treatment online

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100% online
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Licensed prescribers

We’re in-network with 100+ insurance plans

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Photo of psychiatrist viewing a laptop

How postpartum depression treatment works at Talkiatry

We make it easy to access the quality mental health care you deserve for this form of depression.

Online mental health screening

The first step is a brief online form so we can learn more about you and what you’re experiencing. This helps us match you with a psychiatrist who understands your needs.

60-minute psychiatric evaluation

Your first visit is a full 60-minute evaluation so you and your clinician can have an in-depth conversation about what brings you to treatment. They’ll ask questions about your goals, medical history, and if you have a family history of mood disorders like depression or bipolar disorder, or other mental health issues.

Personalized medication plan and follow-up care

You’ll work with your clinician to create a care plan that feels right for you. If they’re recommending medication, they’ll walk you through your options and answer any questions you may have. You’ll continue to check in at regular 30-minute follow-up appointments.

Medications used to treat postpartum depression

There are a variety of medication options for postpartum depression symptoms. Your psychiatrist will work with you to find the best possible treatment for your needs.

SSRIs

Selective Serotonin Reuptake Inhibitors (SSRIs) work to increase the level of serotonin in the brain, a chemical messenger that affects mood, emotion, and sleep. These medications are typically well tolerated, with a lower risk of side effects than other types of antidepressants, and are often the first-line medications for depression.

Common medications:

  • Fluoxetine (Prozac)
  • Escitalopram (Lexapro)
  • Paroxetine (Paxil)
  • Sertraline (Zoloft)
  • Citalopram (Celexa)

SNRIs

Serotonin-norepinephrine reuptake inhibitors (SNRIs) increase the level of both serotonin and another neurotransmitter, norepinephrine, in the brain. Like SSRIs, SNRIs are first-line depression medications that are typically well tolerated.

Common medications:

  • Duloxetine (Cymbalta)
  • Venlafaxine (Effexor)
  • Desvenlafaxine (Pristiq)
  • Milnacipran (Savella)

Atypical antidepressants

There are antidepressants that target different chemicals in the brain than SSRIs or SNRIs, referred to as atypical antidepressants. They can be a good fit if you have experienced side effects from other types of depression medication. They can be taken on their own or in combination with other medications that treat depression symptoms.

Common medications:

  • Bupropion (Wellbutrin)
  • Mirtazapine (Remeron)
  • Vortioxetine (Trintellix)

Medications FDA-approved for postpartum depression

There are two medications specifically approved by the Food and Drug Administration (FDA) for postpartum depression: Zurzuvae, the first oral medication approved to treat PPD, and brexanolone, which requires an infusion in a hospital.

What to consider when breastfeeding

Many psychiatric medications are considered safe to take while breastfeeding, but there are some exceptions. If you’re exploring your treatment options, talk to your psychiatrist about the potential risks and benefits of specific medications. There may be other options to consider, like taking an alternative medication or adjusting your dosing schedule.

Learn more about medications for postpartum depression and which might be best for you.

Why choose online postpartum depression care

Care that’s actually about you

Our psychiatrists take time to understand your experience and create a treatment plan that fits your needs and comfort level.

Flexibility and convenience when it matters most

Virtual appointments fit easily into the first year with a new baby—no commutes, waiting rooms, or rearranging your day.

No surprise bills

We’re in-network with over 100 insurance plans, which means fewer billing surprises and more time to focus on your healing and well-being.

Photo of psychiatrist viewing a laptop
Photo of psychiatrist viewing a laptop

Comprehensive care for real healing

Therapy referrals available

If you’d benefit from other types of care, such as talk therapies including cognitive behavioral therapy (CBT), your psychiatrist can provide recommendations for in person or online providers. In some cases, we can connect you to a therapist within Talkiatry for online therapy.

Check-ins and treatment adjustments

We understand that treatment needs can change, and your care should evolve with them. Your clinician will monitor how you’re feeling at regular follow-ups and adjust your treatment plan as needed.

Care that doesn’t rush you

Recovery from postpartum depression can take time. Your care with us can continue as long as you need it, with flexibility, compassion, and respect for your pace.

Psychiatrists who know perinatal mental health

Our care team includes over 300 licensed psychiatrists, many with deep experience in treating new moms and parents for postpartum depression and postpartum anxiety. We’ll match you with a mental health professional who understands what you’re going through.

  • 300+ expert psychiatrists
  • 1 million+ visits completed
  • 175,000+ patients matched

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Care by the numbers

1 million+

visits completed

300+

expert clinicians

90% of patients

would recommend us to family and friends

What our patients say

“I recommend Talkiatry to anyone that will listen. The benefits this network has provided me in such a short time are priceless and immeasurable.”

Nancy L., Ohio

“She is very relatable. She is mindful of cost of my medications.”

Joseph D., Colorado

“Great experience! Provider was ready early which was amazing and honestly never happens.  Really appreciate honoring a patient’s time.”

Jennifer C., Texas

Additional Postpartum Depression Resources

Postpartum Depression Symptoms

Learn more about how ADHD presents and how it feels.

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Postpartum Depression Diagnosis

ADHD diagnoses are complex and need to come from a qualified clinician.

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Postpartum Depression Treatment

The most common treatments involve medication, therapy, or both.

Learn more ›

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Frequently asked questions

Can I get postpartum depression medication prescribed online?

Yes, licensed psychiatrists can prescribe medication for postpartum depression through a secure online visit. Your treatment plan is personalized, and we’ll work with you to find an option that feels right.

What is the safest medication for postpartum depression?

There’s no one-size-fits-all treatment for postpartum depression, and everyone’s needs are different. There are many effective treatment options, from SSRIs and SNRIs to atypical antidepressants and Zurzuvae. Your psychiatric care provider will work with you to determine the safest and most effective medication for your needs and health history.

Can I take antidepressants while breastfeeding?

In many cases, yes. Most antidepressants pass into breast milk in very small amounts and are considered safe to take while breastfeeding, though there are some exceptions. Your psychiatrist can help you weigh the benefits and risks, and discuss options that align with your breastfeeding goals.

How long does it take for postpartum depression medications to work?

Most antidepressants take a few weeks to start working—often around 2 to 4 weeks for initial effects—but it can take up to 6 to 8 weeks to experience the full effects. Your clinician will check in regularly and make adjustments as needed to ensure you’re on the right track.

What if I’m not sure if what I’m feeling is postpartum depression?

It’s very common for new mothers and parents to be unsure if they’re experiencing symptoms of postpartum depression. Mental health conditions look different for everyone, and moments of mood swings, anxiety, sadness, or overwhelm are to be expected throughout the journey of pregnancy and into the postpartum period. Symptoms of postpartum depression last longer and interfere with daily life much more than the typical “baby blues.” If you’re feeling off, overwhelmed, or not like yourself, a mental health screening can help you get clarity and connect with the right support.

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